Shaf keshavjee biography of william murphy

Jump to navigation. Shaf Keshavjee is a world-renowned thoracic surgeon-scientist with a history of breakthroughs and discoveries in lung transplantation. Keshavjee completed his medical training at the University of Toronto in , and specialized in General Surgery, Cardiac Surgery and Thoracic Surgery. Keshavjee completed fellowships at Harvard University and the University of London.

Keshavjee developed a lung preservation solution for donor lungs that has now been translated into clinical use around the world. For Dr. My lab focuses on the molecular mechanisms of lung preservation, injury and repair. During the six hours that a lung can remain physiologically active on EVLP, surgeons can fully assess physiologic quality and make a more informed and objective decision on whether to utilize the lung for transplant.

Since the time of William

Importantly, the hours during which lungs are on EVLP have also enabled a critical time window in which the team can apply novel, isolated therapies to repair injured donor lungs prior to transplant. To this extent, we are currently developing a number of precision diagnostics and novel repair therapies, including gene therapy and CRISPR-Cas9 applications, that will maximize the potential of EVLP in the transplant clinic.

For a list of Dr. Cell-free DNA in human ex vivo lung perfusate as a potential biomarker to predict the risk of primary graft dysfunction in lung transplantation. J Thorac Cardiovasc Surg. Cypel M, Keshavjee S. Lancet Respir Med. J Surg Res. Lung transplantation for cystic fibrosis.